1017Risk Factors for Post-Operative Infections after Cesarean Section

Background. The objective was to determine the prevalence of post-operative infections after cesarean section and identify modifiable risk factors associated with postcesarean section infections. Methods. Retrospective chart review of patients who underwent a cesarean section between January 1, 2013–June 30, 2014 was conducted at an academic institution. Postoperative infection was defined as any infection within 30 days from date of primary surgery using the CDC criteria as guideline. Chi squarewas used for comparison of all categorical dataandwe reported spearmancorrelationcoefficient.TheStudentT testwasused for continuous variables and p values reported. Univariate analysis was done with significancedeterminedatP < 0.05.VariableswithP < 0.05were thensubsequentlyrunthrougha multivariate analysis. A total of 1,189 charts were included in our final analysis. Results. We had 56% (n = 672) primary and 44% (n = 526) repeat cesarean sections. 47% were scheduled (n = 564), 48% unscheduled (n = 571) and 5% emergent (n = 62). Post-operative infection after cesarean section was 7.6% (n = 91). On univariate analysis, risk factors associated with post-operative infections include primary cesarean section (OR,1.66 [95% CI,1.05-2.63]), Non-Elective cesarean section (OR, 1.92 [1.03-3.57]); sexually transmitted infection in pregnancy (OR, 3.83 [1.50-9.79]), cervical shortening <15cm (OR, 3.72 [1.34-10.33]), PPROM (OR, 5.3 [1.82-15.38]) gestational HTN (OR, 2.38 [1.08-5.23]), asthma (OR, 3.83 [1.50-9.79]), intraoperative estimated blood loss >1,000 mL (OR, 2.27 [1.08-4.77]), Chorioamnionitis, (OR, 2.8 [1.5-5.1], p = .0004), and blood transfusion during the hospital stay (OR, 3.5 [95% CI, 1.5-8.2]). On subgroup analysis, skin closure with staples was associated with increasing rates of wound infection (OR, 1.88 [1.08-3.33]). Continuous or Multi-categorical values associated with post-operative infection were decreasing post-operative hemoglobin (p = 0.0229), length of membrane rupture (<0.0001), increasing BMI (p = 0.0042), Classical Incision (p < 0.0003), any intraoperative complication (p = .0048), and Emergent Surgery (p < 0.001). Conclusion. Study identifies modifiable risk factors for post-operative infection after cesarean section. Identification of these risk factors allows targeted measures to be instituted, resulting in reduced infection rate. Disclosures. All authors: No reported disclosures.